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Inserm Transfert umr 1247 grap
Umr 1247 Grap, supplied by Inserm Transfert, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/umr+1247+grap/inserm+u1016/pm40220857-10-51-51
Average 90 stars, based on 1 article reviews
umr 1247 grap - by Bioz Stars, 2026-09
90/100 stars

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Article Title: Memory and plasticity impairment after binge drinking in adolescent rat hippocampus: GluN2A/GluN2B NMDA receptor subunits imbalance through HDAC2.
Article Snippet: Addiction Biology.. 2019;e12760. https://doi.org/10.1111/adb.12760 Abstract Ethanol (EtOH) induces cognitive impairment through modulation of synaptic plasticity notably in the hippocampus.. The cellular mechanism(s) of these EtOH effects may range from synaptic signaling modulation to alterations of the epigenome.

Drug discovery:

Article Title: Trace amine-associated receptor 1 agonists reduce alcohol drinking and differentially modulate dopamine release in the nucleus accumbens of alcohol preferring mice.
Article Snippet: Current treatments for alcohol use disorder have limited efficacy underscoring the need for novel therapeutic targets.. Trace amine-associated receptor 1 (TAAR1) is a promising candidate due to its ability to act as a brake on dopaminergic transmission and alcohol consumption.. However, both the relative efficacy of full and partial TAAR1 agonists in reducing alcohol-related behaviors and their underlying mechanisms of action remain unclear.

Biomarker Discovery:

Article Title: Trace amine-associated receptor 1 agonists reduce alcohol drinking and differentially modulate dopamine release in the nucleus accumbens of alcohol preferring mice.
Article Snippet: Current treatments for alcohol use disorder have limited efficacy underscoring the need for novel therapeutic targets.. Trace amine-associated receptor 1 (TAAR1) is a promising candidate due to its ability to act as a brake on dopaminergic transmission and alcohol consumption.. However, both the relative efficacy of full and partial TAAR1 agonists in reducing alcohol-related behaviors and their underlying mechanisms of action remain unclear.



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